1,839 research outputs found

    SystemC Model Generation for Realistic Simulation of Networked Embedded Systems

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    Verification and design-space exploration of today's embedded systems require the simulation of heterogeneous aspects of the system, i.e., software, hardware, communications. This work shows the use of SystemC to simulate a model-driven specification of the behavior of a networked embedded system together with a complete network scenario consisting of the radio channel, the IEEE 802.15.4 protocol for wireless personal area networks and concurrent traffic sharing the medium. The paper describes the main issues addressed to generate SystemC modules from Matlab/Stateflow descriptions and to integrate them in a complete network scenario. Simulation results on a healthcare wireless sensor network show the validity of the approach

    Compression modes in nuclei: microscopic models with Skyrme interactions

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    The isoscalar giant monopole resonances (ISGMR) and giant dipole resonances (ISGDR) in medium-heavy nuclei are investigated in the framework of HF+RPA and HF-BCS+QRPA with Skyrme effective interactions. It is found that pairing has little effect on these modes. It is also found that the coupling of the RPA states to 2p-2h configurations results in about (or less than) 1 MeV shifts of the resonance energies and at the same time gives the correct total widths. For the ISGMR, comparison with recent data leads to a value of nuclear matter compression modulus close to 215 MeV. However, a discrepancy between calculated and measured energies of the ISGDR in 208^{208}Pb is found and remains an open problem.Comment: To appear in: ``RIKEN Symposium and Workshop on Selected Topics in Nuclear Collective Excitations'', proceedings of the meeting, RIKEN, Wako city (Japan), March 20--24, 199

    Calibração de um lisímetro simplificado de pesagem.

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    O crescente uso da água e a redução de sua disponibilidade têm se tornado preocupação cada vez maior em todo o mundo. Em termos mundiais, a agricultura é responsável pela utilização de 70% da água doce consumida no planeta, por isso tem sido alvo de crítica pela sociedade demandando que sua utilização seja da forma mais racional possível. O presente trabalho tem como objetivo a construção e calibração de um lisímetro de pesagem em solo não vegetado de custo reduzido

    Temperature and precipitation seasonal forecasts over the Mediterranean region: added value compared to simple forecasting methods

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    This study considers a set of state-of-the-art seasonal forecasting systems (ECMWF, MF, UKMO, CMCC, DWD and the corresponding multi-model ensemble) and quantifies their added value (if any) in predicting seasonal and monthly temperature and precipitation anomalies over the Mediterranean region compared to a simple forecasting method based on the ERA5 climatology (CTRL) or the persistence of the ERA5 anomaly (PERS). This analysis considers two starting dates, May 1st and November 1st and the forecasts at lead times up to 6 months for each year in the period 1993–2014. Both deterministic and probabilistic metrics are employed to derive comprehensive information on the forecast quality in terms of association, reliability/resolution, discrimination, accuracy and sharpness. We find that temperature anomalies are better reproduced than precipitation anomalies with varying spatial patterns across different forecast systems. The Multi-Model Ensemble (MME) shows the best agreement in terms of anomaly correlation with ERA5 precipitation, while PERS provides the best results in terms of anomaly correlation with ERA5 temperature. Individual forecast systems and MME outperform CTRL in terms of accuracy of tercile-based forecasts up to lead time 5 months and in terms of discrimination up to lead time 2 months. All seasonal forecast systems also outperform elementary forecasts based on persistence in terms of accuracy and sharpness

    Usage personnel de pratiques relevant des médecines douces ou alternatives parmi les médecins suisses

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    L'importance de l'utilisation pour des besoins personnels de pratiques relevant des médecines douces ou alternatives parmi les médecins est très mal connue. Elle pourrait avoir plusieurs implications notamment par rapport à l'effort actuel de promotion de pratiques médicales fondées sur des preuves d'efficacité (Evidence-based medicine, EBM). [Auteurs]]]> fre oai:serval.unil.ch:BIB_F32E44E67757 2022-05-07T01:30:01Z openaire documents urnserval <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_F32E44E67757 PAX5 activates the transcription of the human telomerase reverse transcriptase gene in B cells. info:doi:10.1002/path.2620 info:eu-repo/semantics/altIdentifier/doi/10.1002/path.2620 info:eu-repo/semantics/altIdentifier/pmid/19806612 Bougel, Stephanie Renaud, Stephanie Braunschweig, Richard Loukinov, Dmitri Morse Herbert C. III, Bosman Fred, T. Lobanenkov, Victor Benhattar, Jean info:eu-repo/semantics/article article 2010 Journal of Pathology, vol. 220, no. 1, pp. 87-96 info:eu-repo/semantics/altIdentifier/pissn/1096-9896[electronic] <![CDATA[Telomerase is an RNA-dependent DNA polymerase that synthesizes telomeric DNA. Its activity is not detectable in most somatic cells but it is reactivated during tumorigenesis. In most cancers, the combination of hTERT hypermethylation and hypomethylation of a short promoter region is permissive for low-level hTERT transcription. Activated and malignant lymphocytes express high telomerase activity, through a mechanism that seems methylation-independent. The aim of this study was to determine which mechanism is involved in the enhanced expression of hTERT in lymphoid cells. Our data confirm that in B cells, some T cell lymphomas and non-neoplastic lymph nodes, the hTERT promoter is unmethylated. Binding sites for the B cell-specific transcription factor PAX5 were identified downstream of the ATG translational start site through EMSA and ChIP experiments. ChIP assays indicated that the transcriptional activation of hTERT by PAX5 does not involve repression of CTCF binding. In a B cell lymphoma cell line, siRNA-induced knockdown of PAX5 expression repressed hTERT transcription. Moreover, ectopic expression of PAX5 in a telomerase-negative normal fibroblast cell line was found to be sufficient to activate hTERT expression. These data show that activation of hTERT in telomerase-positive B cells is due to a methylation-independent mechanism in which PAX5 plays an important role
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